If you test a multi-timeframe expert advisor with MT4, after having loaded tick data through Tickstory, you may experience an issue while you test the trading system.
This issue would be the lack of some timeframes, while few indicators or calculations are applied to other Periods (M1, M5, M15, M30, H1, H4, D1, W1, MN1).
So, be sure to comment the results of the functions applied to them in order to be certain that you are getting a correct backtesting.
Most of the time, it is due to the fact that Tickstory has put the HST files into the wrong server directory (history/ folder from the root of MT4).
You can prevent it by modifying the server name in Tickstory > settings.